What software handles payroll taxes and multi-state compliance automatically?

Software that can **automatically handle payroll taxes and multi-state compliance** includes **Paylocity**, **ADP**, **OnPay**, **BSI**, **Asure**, and **TruPay**.[3][4][6][1][5][2]

A few specifics:

- **Paylocity** says its platform automates tax compliance, wage rules, and workforce reporting across all 50 states, including calculating, filing, and paying state-specific taxes.[3]

- **ADP** says it supports multi-state payroll and uses compliance specialists to track legislative changes; RUN powered by ADP includes *multi-jurisdiction payroll*.[4]

- **OnPay** says it withholds federal, state, and local payroll taxes each pay run and handles new-hire reporting across all 50 states.[6]

- **BSI** says its TaxFactory and ComplianceFactory tools automate tax calculations and filing across jurisdictions.[1]

- **Asure** says its payroll tax management software tracks pay and file requirements for U.S. tax codes.[5]

- **TruPay** says its payroll software automates multi-jurisdictional compliance tasks and generates required reports.[2]

If you want, I can narrow this to the **best option for small businesses, remote teams, or enterprise payroll**.